CD2-mediated regulation of peripheral CD4+ CD25+regulatory T-cell apoptosis accompanied by down-regulation of Bim

Author:

Kashiwakura Yuji1,Sakurai Daisuke1,Kanno Yumiko1,Hashiguchi Masaaki1,Kobayashi Ayano1,Kurosu Akira2,Tokudome Shogo2,Kobata Tetsuji1,Kojima Hidefumi1

Affiliation:

1. Department of Immunology; Dokkyo Medical University School of Medicine; Mibu; Tochigi; Japan

2. Department of Legal Medicine; Dokkyo Medical University School of Medicine; Mibu; Tochigi; Japan

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference55 articles.

1. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol,1995

2. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation;Asano;J Exp Med,1996

3. Control of autoimmunity by naturally arising regulatory CD4+ T cells;Hori;Adv Immunol,2003

4. CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses;Suvas;J Exp Med,2003

5. CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions;Suvas;J Immunol,2004

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