Frequency and risk factors of atrial fibrillation after acute abdominal surgery: A prospective cohort study

Author:

Madsen Christoffer L.12ORCID,Leerhøy Bonna3,Jørgensen Lars N.3,Meyhoff Christian S.45,Sajadieh Ahmad1,Domínguez Helena12

Affiliation:

1. Department of Cardiology Copenhagen University Hospital – Bispebjerg and Frederiksberg Copenhagen Denmark

2. Department of Biomedical Sciences University of Copenhagen Copenhagen Denmark

3. Digestive Disease Centre Copenhagen University Hospital – Bispebjerg and Frederiksberg Copenhagen Denmark

4. Department of Anaesthesia and Intensive Care Copenhagen University Hospital – Bispebjerg and Frederiksberg Copenhagen Denmark

5. Department of Clinical Medicine University of Copenhagen Copenhagen Denmark

Abstract

AbstractBackground and AimScarce data exist on the true incidence of postoperative atrial fibrillation (POAF) after acute abdominal surgery and associated outcomes. The current study aimed to identify the frequencies of clinically recognized POAF and associated complications, along with their risk factors.MethodsThis study was a prospective, single‐center cohort study of unselected adult patients referred for acute abdominal surgery during a 3‐month period. Through careful review, demographics, comorbidity, and surgical characteristics were prospectively drawn from medical charts. The primary outcome was clinically recognized POAF occurring in‐hospital. Logistic regression was used to determine the risk factors of POAF and associated complications. A subgroup was enrolled in a feasibility study of peri‐ and postoperative continuous cardiac rhythm monitoring.ResultsIn total, 450 patients were enrolled. Clinically recognized in‐hospital POAF was observed in 22 patients (4.9%). All cases were observed in patients aged ≥60 years, corresponding to 22 of 164 patients (13.4%). Multiple risk factors were observed, such as age, prior atrial fibrillation, heart failure, hypertension, diabetes mellitus, chronic renal disease, and major (vs. minor) surgery. POAF was associated with severe in‐hospital complications (POAF group 45.5% vs. non‐POAF group 8.6%, p < .001) and in‐hospital mortality (POAF group 13.6% vs. non‐POAF group 3.0%, p = .043). In total, 295 patients were monitored by continuous cardiac rhythm monitoring for 12,148 h, yielding five patients with asymptomatic AF.ConclusionsIn conclusion, this prospective study of POAF in patients undergoing acute abdominal surgery showed that one in 20 patients developed clinically recognized in‐hospital POAF. Multiple risk factors of POAF were identified. POAF was associated with severe complications up to 30 days after surgery.

Funder

Danmarks Frie Forskningsfond

IMK Almene Fond

Novo Nordisk Fonden

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine,General Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3