SAPHO syndrome complicated with relapsing polychondritis: A case report

Author:

Cao Fengjiao1,Hou Xiujuan1,Kang Tianlun1ORCID,Shi Xiaojun1,Ma Weiguo1,Zhang Yuan2,Li Chen2ORCID

Affiliation:

1. Department of Rheumatology Dongfang Hospital Beijing University of Chinese Medicine Beijing China

2. Department of Rheumatology Fangshan Hospital Beijing University of Chinese Medicine Beijing China

Abstract

AbstractSynovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disease. The main clinical manifestation of SAPHO syndrome is an osteoarthropathy with cutaneous involvement. Relapsing polychondritis (RP) characterized by chronic inflammation and cartilage degeneration is a rare systematic autoimmune disease. Here we report a RP case in a SAPHO syndrome patient, in which auricularitis happened 10 years after the diagnosed as SAPHO syndrome. Tofacitinib treatment can alleviate the symptoms.

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Rheumatology

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Tofacitinib for the treatment of severe rare skin diseases: a narrative review;European Journal of Clinical Pharmacology;2024-01-17

2. JAKi: Can it be used to treat SAPHO syndrome?;International Journal of Rheumatic Diseases;2023-10-02

3. Unusual cause of inflammatory backache: SAPHO syndrome;International Journal of Rheumatic Diseases;2023-08-17

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