Evaluation of adapted dermocosmetic regimens for perimenopausal and menopausal women using an artificial intelligence‐based algorithm and quality of life questionnaires: An open observational study

Author:

Flament Frederic1ORCID,Jiang Ruowei2,Delaunay Caroline1,Kerob Delphine3,Leclerc‐Mercier Stéphanie4,Kosmadaki Marita5,Roó Elia6,Haag Thierry7,Passeron Thierry89,Zouboulis Christos C.10111213

Affiliation:

1. L'Oréal Research and Innovation Clichy France

2. ModiFace – A L'Oréal Group Company Toronto Canada

3. Cosmetic Active International Levallois Perret France

4. Laboratoires Vichy Levallois Perret France

5. Dermoiatriki Athens Greece

6. Clider Clínica Dermatológica Roó Universidad Francisco de Vitoria Madrid Spain

7. Med'well Institute Pôle Santé les Célestins Vichy France

8. Department of Dermatology Université Côte d'Azur, CHU Nice Nice France

9. Université Côte d'Azur, INSERM, U1065, C3M Nice France

10. Departments of Dermatology Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg Dessau Germany

11. Department of Venereology Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg Dessau Germany

12. Department of Allergology Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg Dessau Germany

13. Department of Immunology Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg Dessau Germany

Abstract

AbstractBackgroundThe decline in estrogen levels from several years before (perimenopause) and during menopause has various negative effects, including skin specific issues, which often receive less attention than other menopausal symptoms despite having a significant negative effect on quality of life (QoL). The objective of this study was to evaluate the effectiveness of anti‐aging dermocosmetic products designed for women during the perimenopause and menopause.Materials and methodsAn open study of 101 perimenopausal women (no menstruation for 4–12 months or irregular menstruation for <5 years) and 101 menopausal women (no menstruation for >12 months), not taking hormone replacement therapy, was conducted. Adapted dermocosmetic regimens, specific to each group (day cream, night cream and serum), were applied for 56 days. Assessments included automatic artificial intelligence diagnostics of eight clinical facial signs, hydration and transepidermal water loss (TEWL), and a menopause skin QoL questionnaire.ResultsMean age was 50 ± 3.9 years (range 41–57) and 59 ± 3.8 years (range 50–66) for the perimenopause and menopause groups, respectively. Significant improvements in wrinkles and vascular signs, increases in hydration, decreases in TEWL, and a positive impact on QoL were observed after 56 days of application of the respective dermocosmetic regimens for both the perimenopause and menopause groups.ConclusionThe anti‐aging skin care products designed specifically for perimenopausal and menopausal women increased skin hydration and improved wrinkles with a positive impact on QoL.

Publisher

Wiley

Subject

Dermatology

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