Affiliation:
1. Department of Small Animal Clinical Sciences Virginia‐Maryland College of Veterinary Medicine Blacksburg Virginia USA
Abstract
AbstractErroneous thyroid function test results can occur because of drugs that alter thyroid hormone physiology in one or more aspects, including synthesis, secretion, distribution, and metabolism. Research since publication of the last review in the Journal of Veterinary Internal Medicine (JVIM) 20 years ago has evaluated the effects of amiodarone, zonisamide, inhalant anesthetics, clomipramine, trilostane, and toceranib on thyroid function tests in the dog. In addition, recent work on the effects of glucocorticoids, sulfonamides, phenobarbital, and nonsteroidal anti‐inflammatory drugs will be reviewed. Awareness of these effects is necessary to avoid misdiagnosis of hypothyroidism and unnecessary treatment.
Reference148 articles.
1. Measurement of serum total thyroxine, triiodothyronine, free thyroxine, and thyrotropin concentrations for diagnosis of hypothyroidism in dogs;Peterson ME;J Am Vet Med Assoc,1997
2. Thyroid‐stimulating hormone and total thyroxine concentrations in euthyroid, sick euthyroid and hypothyroid dogs
3. Comparison of serum concentrations of thyroid‐stimulating hormone in healthy dogs, hypothyroid dogs, and euthyroid dogs with concurrent disease;Scott‐Moncrieff JC;J Am Vet Med Assoc,1998
4. Evaluation of serum free thyroxine and thyrotropin concentrations in the diagnosis of canine hypothyroidism
5. Effects of age, sex, and body size on serum concentrations of thyroid and adrenocortical hormones in dogs;Reimers TJ;Am J Vet Res,1990