Addressing phenoconversion: the Achilles' heel of personalized medicine

Author:

Shah Rashmi R.1,Smith Robert L.2

Affiliation:

1. Rashmi Shah Consultancy Ltd; Gerrards Cross UK

2. Department of Surgery and Cancer; Faculty of Medicine; Imperial College; London UK

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference147 articles.

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2. A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants;Sim;Clin Pharmacol Ther,2006

3. Individualized medicine - implementation of pharmacogenetic diagnostics in antidepressant drug treatment of major depressive disorders;Kirchheiner;Pharmacopsychiatry,2003

4. Genetic variations in eleven phase I drug metabolism genes in an ethnically diverse population;Solus;Pharmacogenomics,2004

5. Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1;Ozawa;Drug Metab Pharmacokinet,2004

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