Heart of the matter—infection and xenotransplantation-Reference-Cited by-同舟云学术

Heart of the matter—infection and xenotransplantation

Published:2023-12-06 Issue: Volume: Page:
ISSN:1398-2273
Container-title:Transplant Infectious Disease
language:en
Short-container-title:Transplant Infectious Dis

Author:

Saharia Kapil K.¹^ORCID,Hall Victoria G.²³^ORCID,Chesdachai Supavit⁴^ORCID,Porrett Paige⁵^ORCID,Fishman Jay A.⁶^ORCID,Pouch Stephanie M.⁷^ORCID,

Affiliation:

1. Institute of Human Virology, Division of Infectious Diseases University of Maryland School of Medicine Baltimore Maryland USA

2. Sir Peter MacCallum Department of Oncology University of Melbourne Parkville Australia

3. Department of Infectious Diseases Peter MacCallum Cancer Centre Melbourne Australia

4. Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine Mayo Clinic Rochester Minnesota USA

5. University of Alabama at Birmingham Heersink School of Medicine Birmingham Alabama USA

6. Transplant Infectious Disease and Compromised Host Program, MGH Transplant Center Massachusetts General Hospital and Harvard Medical School Boston Massachusetts USA

7. Division of Infectious Diseases Emory University School of Medicine Atlanta Georgia USA

Abstract

AbstractIn this clinicopathological conference, invited experts discussed a previously published case of a patient with nonischemic cardiomyopathy who underwent heart transplantation from a genetically modified pig source animal. His complex course included detection of porcine cytomegalovirus by plasma microbial cell‐free DNA and eventual xenograft failure. The objectives of the session included discussion of selection of immunosuppressive regimens and prophylactic antimicrobials for human xenograft recipients, description of infectious disease risk assessment and mitigation in potential xenograft donors and understanding of screening and therapeutic strategies for potential xenograft‐related infections.

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Publisher

Wiley

Subject

Infectious Diseases,Transplantation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/tid.14206

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2. First clinical-grade porcine kidney xenotransplant using a human decedent model

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