Mucoepidermoid carcinoma cured by a combination of high‐frequency snare and photodynamic therapy: A case report

Author:

Tamura Kentaro123ORCID,Uchimura Keigo1ORCID,Furuse Hideaki1,Imabayashi Tatsuya1ORCID,Matsumoto Yuji12,Tsuchida Takaaki1

Affiliation:

1. Department of Endoscopy, Respiratory Endoscopy Division National Cancer Center Hospital Tokyo Japan

2. Department of Thoracic Oncology National Cancer Center Hospital Tokyo Japan

3. Division of Respiratory Diseases, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan

Abstract

AbstractMucoepidermoid carcinoma (MEC) is a rare salivary gland tumor, accounting for 0.2% of all lung tumors. The standard treatment for MEC of the primary bronchus is surgery, although intraluminal bronchoscopic treatment has recently become an option. A 68‐year‐old man presented with an asymptomatic bronchial tumor in the right intermediate bronchus. The tumor was resected using a high‐frequency snare (HFS) during bronchoscopy, and the specimen was pathologically diagnosed as low‐grade MEC. A residual lesion was detected in the resected area by autofluorescence imaging. The tumor appeared to be localized within the subepithelial layer without metastases, and photodynamic therapy (PDT) was performed as a local treatment. The patient had no recurrence for 18 months. PDT is effective and safe for patients with centrally located early‐stage lung cancer, but there are few reports of its use for rare tumors, such as MEC. In this case, PDT allowed for local control and avoided surgery, including bronchoplasty, for MEC. Combined treatment of tumor reduction by HFS and PDT of the residual lesion may be an optimal treatment for MEC of the bronchus.

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine,Oncology,General Medicine

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