An attention‐based deep learning method for right ventricular quantification using 2D echocardiography: Feasibility and accuracy

Author:

Kampaktsis Polydoros N.1ORCID,Bohoran Tuan A.2,Lebehn Mark1,McLaughlin Laura3,Leb Jay4,Liu Zhonghua5,Moustakidis Serafeim6,Siouras Athanasios6,Singh Anvesha7,Hahn Rebecca T.1,McCann Gerry P.7,Giannakidis Archontis2

Affiliation:

1. Division of Cardiology Department of Medicine Columbia University Irving Medical Center New York New York USA

2. School of Science and Technology Nottingham Trent University Nottingham UK

3. Department of Medicine Columbia University Irving Medical Center New York New York USA

4. Department of Radiology Columbia University Irving Medical Center New York New York USA

5. Department of Biostatistics Columbia University Irving Medical Center New York New York USA

6. AiDEAS Tallinn Estonia

7. Department of Cardiovascular Sciences University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital Leicester UK

Abstract

AbstractAimTo test the feasibility and accuracy of a new attention‐based deep learning (DL) method for right ventricular (RV) quantification using 2D echocardiography (2DE) with cardiac magnetic resonance imaging (CMR) as reference.Methods and ResultsWe retrospectively analyzed images from 50 adult patients (median age 51, interquartile range 32–62 42% women) who had undergone CMR within 1 month of 2DE. RV planimetry of the myocardial border was performed in end‐diastole (ED) and end‐systole (ES) for eight standardized 2DE RV views with calculation of areas. The DL model comprised a Feature Tokenizer module and a stack of Transformer layers. Age, gender and calculated areas were used as inputs, and the output was RV volume in ED/ES. The dataset was randomly split into training, validation and testing subsets (35, 5 and 10 patients respectively).Mean RVEDV, RVESV and RV ejection fraction (EF) were 163 ± 70 mL, 82 ± 42 mL and 51% ± 8% respectively without differences among the subsets. The proposed method achieved good prediction of RV volumes (R2 = .953, absolute percentage error [APE] = 9.75% ± 6.23%) and RVEF (APE = 7.24% ± 4.55%). Per CMR, there was one patient with RV dilatation and three with RV dysfunction in the testing dataset. The DL model detected RV dilatation in 1/1 case and RV dysfunction in 4/3 cases.ConclusionsAn attention‐based DL method for 2DE RV quantification showed feasibility and promising accuracy. The method requires validation in larger cohorts with wider range of RV size and function. Further research will focus on the reduction of the number of required 2DE to make the method clinically applicable.

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging

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