Review article: Why is there still a debate regarding the safety and efficacy of intravenous thrombolysis in the management of presumed acute ischaemic stroke? A systematic review and meta-analysis

Author:

Donaldson Lachlan1,Fitzgerald Emily12,Flower Oliver13,Delaney Anthony134

Affiliation:

1. Malcolm Fisher Department of Intensive Care Medicine, Royal North Shore Hospital; Sydney New South Wales Australia

2. Faculty of Health; University of Technology Sydney; Sydney New South Wales Australia

3. Northern Clinical School, Sydney Medical School; The University of Sydney; Sydney New South Wales Australia

4. ANZIC Research Centre, Department of Epidemiology and Preventative Medicine; Monash University; Melbourne Victoria Australia

Publisher

Wiley

Subject

Emergency Medicine

Reference78 articles.

1. Therapeutic thrombolysis in cerebral thromboembolism: double-blided evaluation of intravenous plasmin therapy in carotid and middle cerebral arterial occlusion;Meyer;Neurology,1963

2. Clinical utility of urokinase in the treatment of acute stage cerebral thrombosis: multi-center double blind study in comparison with placebo;Atarashi;Clin. Eval.,1985

3. Randomised controlled trial of streptokinase, aspirin, and combination of both in treatment of acute ischaemic stroke;Multicentre Acute Stroke Trial--Italy (MAST-I) Group;Lancet,1995

4. Pilot randomized trial of tissue plasminogen activator in acute ischemic stroke;Haley;The TPA Bridging Study Group. Stroke,1993

5. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients;Fibrinolytic Therapy Trialists' (FTT) Collaborative Group;Lancet,1994

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