The prognostic significance of the aberrant extremes of p53 immunophenotypes in breast cancer

Author:

Boyle David P1,McArt Darragh G1,Irwin Gareth1,Wilhelm-Benartzi Charlotte S2,Lioe Tong F3,Sebastian Elena1,McQuaid Stephen1,Hamilton Peter W1,James Jacqueline A1,Mullan Paul B1,Catherwood Mark A4,Harkin D Paul1,Salto-Tellez Manuel1

Affiliation:

1. Centre for Cancer Research and Cell Biology; Queen's University Belfast; Belfast UK

2. Epigenetics Unit; Department of Surgery and Cancer; Imperial College; London UK

3. Department of Histopathology; Belfast City Hospital; Belfast UK

4. Department of Haematology; Belfast City Hospital; Belfast UK

Funder

Pathological Society of Great Britain and Ireland

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Reference36 articles.

1. Cancer. p53, guardian of the genome;Lane;Nature,1992

2. p53: the most frequently altered gene in human cancers;Vogelstein;Nat. Educ.,2010

3. The rebel angel: mutant p53 as the driving oncogene in breast cancer;Walerych;Carcinogenesis,2012

4. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer;Forbes;Nucleic Acids Res.,2010

5. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer;Harris;J. Clin. Oncol.,2007

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