Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity-Reference-Cited by-同舟云学术

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Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity

Published:2016-03-02 Issue:1 Volume:137 Page:88-100
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:J. Neurochem.

Author:

Falker Clemens¹,Hartmann Alexander¹,Guett Inga¹,Dohler Frank¹,Altmeppen Hermann¹,Betzel Christian²³,Schubert Robin²³,Thurm Dana¹,Wegwitz Florian⁴,Joshi Pooja⁵,Verderio Claudia⁵⁶,Krasemann Susanne¹,Glatzel Markus¹

Affiliation:

1. Institute of Neuropathology; University Medical Center Hamburg-Eppendorf; Hamburg Germany

2. Laboratory of Structural Biology of Infection and Inflammation; Institute of Biochemistry and Molecular Biology; University of Hamburg; Hamburg Germany

3. The Hamburg Centre for Ultrafast Imaging; Hamburg Germany

4. Department of Translational Cancer Research; University Medical Center Göttingen; Göttingen Germany

5. IRCCS Humanitas; Rozzano Italy

6. CNR-Institute of Neuroscience; Milano Italy

Funder

Deutsche Forschungsgemeinschaft

PIER grant from DESY and the University of Hamburg

Seventh Framework Programme

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.13514/fullpdf

Reference67 articles.

1. Measurement of top quark polarization in top-antitop events from proton-proton collisions at radicals=7 TeV using the ATLAS detector;Aad;Phys. Rev. Lett.,2013

2. Myeloid microvesicles in cerebrospinal fluid are associated with myelin damage and neuronal loss in mild cognitive impairment and Alzheimer disease;Agosta;Ann. Neurol.,2014

3. Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo;Altmeppen;Mol. Neurodegener.,2011

4. Roles of endoproteolytic alpha-cleavage and shedding of the prion protein in neurodegeneration;Altmeppen;FEBS J.,2013

5. The sheddase ADAM10 is a potent modulator of prion disease;Altmeppen;Elife,2015

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