Histological, morphometric, protein and gene expression analyses of rat retinas with ischaemia-reperfusion injury model treated with sildenafil citrate

Author:

Zanoni Diogo S.1ORCID,Da Silva Germana A.2,Ezra-Elia Raaya3,Carvalho Márcio1,Quitzan Juliany G.4,Ofri Ron3,Laus José L.2,Laufer-Amorim Renee1

Affiliation:

1. Department of Veterinary Clinic; School of Veterinary Medicine and Animal Science; University Estadual Paulista; Botucatu SP Brazil

2. Department of Veterinary Clinic and Surgery; School of Veterinary Medicine and Animal Science; University Estadual Paulista; Jaboticabal SP Brazil

3. Koret School of Veterinary Medicine; The Hebrew University of Jerusalem; Israel

4. Department of Surgery and Anesthesiology; School of Veterinary Medicine and Animal Science; University Estadual Paulista; Botucatu SP Brazil

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Pathology and Forensic Medicine

Reference44 articles.

1. The molecular basis of retinal ganglion cell death in glaucoma;Almasieh;Prog. Retin. Eye Res.,2012

2. Estimation of prevalence and incidence rates and causes of blindness in Israel, 1998-2003;Avisar;Isr. Med. Assoc. J.,2006

3. Retinal ganglion cell (RGC) programmed necrosis contributes to ischemia-reperfusion induced retinal damage;Dvoriantchikova;Exp. Eye Res.,2014

4. Sildenafil decreased cardiac cell apoptosis in diabetic mice: reduction of oxidative stress as a possible mechanism;Ebrahimi;Can. J. Physiol. Pharmacol.,2009

5. Functional and structural evaluation of sildenafil in a rat model of acute retinal ischemia/reperfusion injury;Ezra-Elia;Curr. Eye Res.,2016

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