AllergoOncology: Opposite outcomes of immune tolerance in allergy and cancer

Author:

Jensen-Jarolim E.12ORCID,Bax H. J.34,Bianchini R.1ORCID,Crescioli S.3,Daniels-Wells T. R.5,Dombrowicz D.6,Fiebiger E.7ORCID,Gould H. J.8,Irshad S.39,Janda J.10,Josephs D. H.34,Levi-Schaffer F.11,O′Mahony L.12ORCID,Pellizzari G.34,Penichet M. L.51314,Redegeld F.15,Roth-Walter F.12,Singer J.2,Untersmayr E.2,Vangelista L.16,Karagiannis S. N.39ORCID

Affiliation:

1. The Interuniversity Messerli Research Institute; University of Veterinary Medicine Vienna; Medical University Vienna; University Vienna; Vienna Austria

2. Centre of Pathophysiology, Infectiology & Immunology; Institute of Pathophysiology & Allergy Research; Medical University Vienna; Vienna Austria

3. St. John's Institute of Dermatology, School of Basic & Medical Biosciences; King's College London; Guy's Hospital; London UK

4. School of Cancer & Pharmaceutical Sciences; King's College London; Guy's Hospital; London UK

5. Division of Surgical Oncology; Department of Surgery; David Geffen School of Medicine at UCLA; Los Angeles CA USA

6. INSERM; CHU Lille; European Genomic Institute of Diabetes; Institut Pasteur de Lille; U1011 - Recepteurs Nucleaires; Maladies Cardiovasculaires et Diabete; Universite de Lille; Lille France

7. Division of Gastroenterology, Hepatology and Nutrition Research; Department Medicine Research; Childrens′ University Hospital Boston; Boston MA USA

8. Randall Division of Cell and Molecular Biophysics; King's College London; London UK

9. Breast Cancer Now Unit; School of Cancer & Pharmaceutical Sciences; King's College London; Guy's Cancer Centre; London UK

10. Faculty of Science; Charles University; Prague Czech Republic

11. Faculty of Medicine; Pharmacology and Experimental Therapeutics Unit; The Institute for Drug Research; School of Pharmacy; The Hebrew University of Jerusalem; Jerusalem Israel

12. Molecular Immunology; Swiss Institute of Allergy and Asthma Research; Davos Switzerland

13. Department of Microbiology, Immunology and Molecular Genetics; David Geffen School of Medicine at UCLA; Los Angeles CA USA

14. Jonsson Comprehensive Cancer Centre; University of California; Los Angeles CA USA

15. Faculty of Science; Division of Pharmacology; Utrecht Institute for Pharmaceutical Sciences; Utrecht University; Utrecht the Netherlands

16. Department of Biomedical Sciences; Nazarbayev University School of Medicine; Astana Kazakhstan

Funder

Academy of Medical Sciences

National Institute for Health Research

Biomedical Research Centre (BRC)

Guy's and St Thomas' NHS Foundation Trust

King’s College London

European Academy for Allergy and Clinical Immunology (EAACI)

Austrian Science Fund

Israel Cancer Association

Israel Science Foundation

Cancer Research UK

Engineering and Physical Sciences Research Council

Medical Research Council

Breast Cancer Now

National Institutes of Health

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference121 articles.

1. Natural regulatory T cells in infectious disease;Belkaid;Nat Immunol,2005

2. The regulation of IL-10 production by immune cells;Saraiva;Nat Rev Immunol,2010

3. Mechanisms of allergen-specific immunotherapy: multiple suppressor factors at work in immune tolerance to allergens;Akdis;J Allergy Clin Immunol,2014

4. Adaptive immunity maintains occult cancer in an equilibrium state;Koebel;Nature,2007

5. Effects of malignant melanoma initiating cells on T-cell activation;Schatton;Methods Mol Biol,2016

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