Detection of in vivo hepatitis B virus surface antigen mutations-A comparison of four routine screening assays

Author:

Gencay M.1,Seffner A.2,Pabinger S.3,Gautier J.4,Gohl P.5,Weizenegger M.2,Neofytos D.1,Batrla R.1,Woeste A.6,Kim H. S.7,Westergaard G.1,Reinsch C.8,Brill E.5,Thuy P. T. T.9,Hoang B. H.10,Sonderup M.11,Spearman C. W.11,Brancaccio G.12,Fasano M.13,Gaeta G. B.12,Santantonio T.13,Kaminski W. E.5ORCID

Affiliation:

1. Roche Diagnostics International Ltd; Rotkreuz Switzerland

2. Department of Molecular Genetics and Microbiology; MVZ Labor Dr. Limbach & Kollegen GbR; Heidelberg Germany

3. Health and Environment Department; Molecular Diagnostics; Austrian Institute of Technology; Vienna Austria

4. Cerba Spécimen Services; Saint-Ouen l’Aumône France

5. Bioscientia; Institute for Medical Diagnostics GmbH; Ingelheim Germany

6. Roche Diagnostics GmbH; Penzberg Germany

7. Department of Laboratory Medicine; Yonsei University College of Medicine; Severance Hospital; Seoul Korea

8. Roche Diagnostics GmbH; Mannheim Germany

9. Hepatology Department; Medic Medical Center; Ho Chi Minh City Vietnam

10. Gastroenterology Department; Ho Chi Minh City University Medical Center; Ho Chi Minh City Vietnam

11. Division of Hepatology and Department of Medicine; University of Cape Town and Groote Schuur Hospital; Cape Town South Africa

12. Infectious Diseases and Viral Hepatitis Unit; University of Campania Luigi Vanvitelli; Naples Italy

13. Infectious Diseases Unit; Department of Clinical and Experimental Medicine; University of Foggia; Foggia Italy

Funder

Roche Diagnostics International Ltd

Publisher

Wiley

Subject

Virology,Infectious Diseases,Hepatology

Reference45 articles.

1. WHO Hepatitis B factsheet 2017 http://www.who.int/mediacentre/factsheets/fs204/en/

2. Prevalence and trend of major transfusion-transmissible infections among blood donors in Western China, 2005 through 2010;Song;PLoS ONE,2014

3. Progress toward prevention of transfusion-transmitted hepatitis B and hepatitis C infection-sub-Saharan Africa, 2000-2011;Apata;Morb Mortal Wkly Rep,2014

4. Sequence analysis of the S gene region in HBV DNA from patients positive for both HBsAg and HBsAb tests;Wang;Hepatol Res,2010

5. Hepatitis B virus surface protein mutations clustered mainly in CTL immune epitopes in chronic carriers: results of an Iranian nationwide study;Khedive;J Viral Hepat,2013

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