Body mass index z‐scores in the first 2 years of life were associated with adverse metabolic and anthropometric outcomes at 3 years of age

Author:

Jakobsen Mikala E.12ORCID,Stentebjerg Louise L.13,Tanvig Mette H.4,Jørgensen Jan S.34,Ovesen Per G.567,Christesen Henrik T.38,Jensen Dorte M.134,Vinter Christina A.134

Affiliation:

1. Steno Diabetes Center Odense Odense University Hospital Odense Denmark

2. The National Research Center for the Working Environment Copenhagen Denmark

3. Department of Clinical Research University of Southern Denmark Odense Denmark

4. Department of Gynecology and Obstetrics Odense University Hospital Odense Denmark

5. Department of Obstetrics and Gynecology Aarhus University Hospital Aarhus Denmark

6. Department of Clinical Medicine Aarhus University Hospital Aarhus Denmark

7. Steno Diabetes Center Aarhus Aarhus University Hospital Aarhus Denmark

8. Hans Christian Andersen Children's Hospital Odense University Hospital Odense Denmark

Abstract

AbstractAimWe investigated associations between body mass index (BMI) z‐scores for children aged 0–2 years and the BMI z‐scores, body fat percentage and metabolic risk factors at 3 years of age.MethodsThis was a secondary analysis of the Lifestyle in Pregnancy and Offspring randomised controlled trial, carried out at two university hospitals in Denmark. It comprised 149 mothers with BMI ≥30 kg/m2 who did or did not receive a lifestyle intervention during pregnancy and a reference group of 97 mothers with normal‐weight, with follow‐up of their 3‐year‐old offspring. The children in these three groups were pooled for the data analyses, due to similar characteristics between groups. The BMI z‐scores were calculated at 5 weeks, 5 months and 1, 2 and 3 years, using Danish reference groups. Their anthropometrics and metabolic outcomes were examined at 3 years of age.ResultsBMI z‐scores at 5 months to 2 years were associated with BMI z‐scores and body fat percentage at 3 years of age and BMI z‐scores were not associated with metabolic risk factors at 3 years.ConclusionBMI z‐scores from 5 weeks of age were associated with adverse anthropometric outcomes but not with metabolic risk factors at 3 years of age.

Publisher

Wiley

Subject

General Medicine,Pediatrics, Perinatology and Child Health

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