Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function

Author:

Zhang Shunxian12,Xu Wanfu12ORCID,Wang Hongli2,Cao Meiwan2,Li Musheng2,Zhao Junhong2,Hu Yan3,Wang Yaodong4,Li Songyu5,Xie Yuanwen6,Chen Guanhua2,Liu Ruitao2,Cheng Yang12,Xu Zhaohui2,Zou Kejian7,Gong Sitang12,Geng Lanlan12

Affiliation:

1. Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center Guangzhou Medical University Guangzhou China

2. Department of Gastroenterology, Guangzhou Women and Children’s Medical Center Guangzhou Medical University Guangzhou China

3. Department of Anesthesiology Hainan General Hospital Haikou China

4. Department of Gastroenterology Kunshan affiliated Hospital of Nanjing University of Chinese Medicine Kunshan China

5. Department of Clinical Laboratory Qionghai Hospital of Traditional Chinese Medicine Qionghai China

6. Department of Anorectal Qionghai Hospital of Traditional Chinese Medicine Qionghai China

7. Department of General Surgery Hainan General Hospital Haikou China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

China Postdoctoral Science Foundation

Natural Science Foundation of Hainan Province

Publisher

Wiley

Subject

Cell Biology,General Medicine

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