Investigation of ocular surface parameters in dogs with different cephalic conformations using veterinary ocular surface analyzer (OSA‐VET)

Author:

Li Yan‐Hui12ORCID,Martins Bianca3ORCID,Lin Chung‐Tien12ORCID

Affiliation:

1. Institute of Veterinary Clinical Sciences, School of Veterinary Medicine National Taiwan University Taipei Taiwan

2. Department of Ophthalmology National Taiwan University Veterinary Hospital Taipei Taiwan

3. Department of Surgical and Radiological Science, School of Veterinary Medicine University of California Davis California USA

Abstract

AbstractObjectiveTo compare ocular surface parameters in dogs with different cephalic conformations and evaluate correlations among tests.Animals StudiedSixty‐eight privately owned dogs.ProceduresThe study categorized canine eyes into three groups based on the craniofacial ratio (CFR): brachycephaly (≤0.52), mesocephaly (>0.52 to <0.67), and dolichocephaly (≥0.67). All eyes were examined using an ocular surface analyzer (OSA‐VET) to determine lipid layer thickness (LLT) of the tear film, tear meniscus height (TMH), non‐invasive tear breakup time (NIBUT), and meibomian gland loss rate of the lower eyelids (MGLRL). Schirmer tear test 1 (STT‐1) and tear film breakup time (TBUT) were also performed. Statistical analyses involved one‐way ANOVA, Kruskal–Wallis H test, post hoc Holm–Sidak test, and Pearson correlation coefficient.ResultsWhile STT‐1 showed no significant difference among dog groups, brachycephalic dogs had significantly lower values in TBUT, NIBUT, and LLT, and a higher TMH, compared to mesocephalic and dolichocephalic dogs. Additionally, brachycephalic dogs exhibited a significantly higher MGLRL than dolichocephalic dogs. Correlations among tests were generally weak to moderate (r < .6) except for a strong correlation between CFR and LLT (r = .641, p < .001), and between TBUT and NIBUT (r = .899, p < .001).ConclusionsBrachycephalic morphology predisposes dogs to a significantly thinner lipid layer and diminished tear film stability, likely due to factors such as impaired meibomian gland function and increased ocular exposure compared to other cephalic conformations, thereby increasing their risk of keratoconjunctivitis sicca (KCS). OSA‐VET shows a valuable tool to provide more comprehensive and precise diagnosis for canine ocular surface disorders.

Publisher

Wiley

Reference39 articles.

1. Addressing brachycephalic ocular syndrome in the dog;Plummer CE;Today's Vet Pract,2015

2. II‐dry eye disease and pigmentary keratitis in brachycephalic dogs‐a brief review;Sooryadas S;J Indian Vet Assoc Kerala,2019

3. Ophthalmic disorders in a referral population of seven breeds of brachycephalic dogs: 970 cases (2008–2017)

4. Clinical signs of brachycephalic ocular syndrome in 93 dogs

5. TFOS DEWS II Definition and Classification Report

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