A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins

Author:

Julve Parreño Jose Manuel1,Huet Estefanía1,Fernández-del-Carmen Asun1,Segura Alvaro2,Venturi Micol1,Gandía Antoni1,Pan Wei-song1,Albaladejo Irene1,Forment Javier1,Pla Davinia3,Wigdorovitz Andrés4,Calvete Juan J.3,Gutiérrez Carlos5,Gutiérrez José María2,Granell Antonio1,Orzáez Diego1

Affiliation:

1. Instituto de Biología Molecular y Celular de Plantas (IBMCP); Agencia Estatal Consejo Superior de Investigaciones Científicas; Universidad Politécnica de Valencia; Valencia Spain

2. Instituto Clodomiro Picado; Facultad de Microbiología; Universidad de Costa Rica; San José Costa Rica

3. Instituto de Biomedicina de Valencia; Agencia Estatal Consejo Superior de Investigaciones Científicas; Valencia Spain

4. Instituto de Virología; CICVyA; INTA; Hurlingham Buenos Aires Argentina

5. Research Institute of Biomedical and Health Sciences; University of Las Palmas de Gran Canaria; Arucas Las Palmas Canary Islands Spain

Funder

Ministerio de Economía y Competitividad

European Regional Development Fund

Publisher

Wiley

Subject

Plant Science,Agronomy and Crop Science,Biotechnology

Reference41 articles.

1. Synthetic biology tackles global antivenom shortage;Arnold;Nature,2016

2. Mining human antibody repertoires;Beerli;MAbs,2010

3. Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma;Bendandi;Ann. Oncol.,2010

4. Toxicity of Costa Rican snake venoms for the white mouse;Bolanos;Am. J. Trop. Med. Hyg.,1972

5. Snake-bites: appraisal of the global situation;Chippaux;Bull. World Health Organ.,1998

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