Estimation of risk of neuropsychiatric adverse events from varenicline, bupropion and nicotine patch versus placebo: secondary analysis of results from the EAGLES trial using Bayes factors

Author:

Beard Emma1ORCID,Jackson Sarah E.1ORCID,Anthenelli Robert M.2,Benowitz Neal L.3ORCID,Aubin Lisa St.4,McRae Thomas4,Lawrence David4,Russ Cristina4,Krishen Alok5,Evins A. Eden6,West Robert1ORCID

Affiliation:

1. Research Department of Behavioural Science and Health University College London London UK

2. Department of Psychiatry University of California San Diego CA USA

3. University of California San Francisco CA USA

4. Pfizer Inc New York NY USA

5. Formerly at GSK, Research Triangle Park NC USA

6. Massachusetts General Hospital and Harvard Medical School Boston MA USA

Funder

Cancer Research UK

Publisher

Wiley

Subject

Psychiatry and Mental health,Medicine (miscellaneous)

Reference18 articles.

1. Pharmacological interventions for smoking cessation: an overview and network meta‐analysis, Cochrane database;Cahill K.;Syst Rev,2013

2. Institute for Safe Medication Practices.QuarterWatch. Monitoring FDA MedWatch Reports: September 24 2014 — Data from 2013 Quarters 2 & 3;2014.

3. Varenicline, Smoking Cessation, and Neuropsychiatric Adverse Events

4. Risk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysis

5. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial

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