Respiratory viruses: New frontiers—a Keystone Symposia report

Author:

Cable Jennifer1,Sun Jie23,Cheon In Su23,Vaughan Andrew E.4,Castro Italo A.5,Stein Sydney R.6,López Carolina B.78,Gostic Katelyn M.9,Openshaw Peter J. M.10,Ellebedy Ali H.11,Wack Andreas12,Hutchinson Edward13,Thomas Mallory M.14,Langlois Ryan A.15,Lingwood Daniel16,Baker Steven F.17,Folkins Melanie18,Foxman Ellen F.19,Ward Andrew B.20,Schwemmle Martin21,Russell Alistair B.22,Chiu Christopher23,Ganti Ketaki24,Subbarao Kanta25,Sheahan Timothy P.26,Penaloza‐MacMaster Pablo27,Eddens Taylor28

Affiliation:

1. PhD Science Writer New York New York USA

2. Division of Pulmonary and Critical Medicine, Department of Medicine; Department of Immunology; and Department of Physiology and Biomedical Engineering Mayo Clinic Rochester Minnesota USA

3. Carter Immunology Center and Division of Infectious Disease and International Health, Department of Medicine University of Virginia Charlottesville Virginia USA

4. University of Pennsylvania School of Veterinary Medicine, Biomedical Sciences Philadelphia Pennsylvania USA

5. Virology Research Center, Ribeirao Preto Medical School University of São Paulo ‐ USP São Paulo Brazil

6. Emerging Pathogens Section, Critical Care Medicine Department, Clinical Center and Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda Maryland USA

7. Department of Pathobiology, School of Veterinary Medicine University of Pennsylvania Philadelphia Pennsylvania USA

8. Department of Molecular Microbiology and Center for Women Infectious Disease Research Washington University School of Medicine St Louis Missouri USA

9. Department of Ecology and Evolution University of Chicago Chicago Illinois USA

10. Department of Respiratory Medicine Imperial College London London UK

11. Department of Pathology and Immunology; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs; and Center for Vaccines and Immunity to Microbial Pathogens Washington University School of Medicine St Louis Missouri USA

12. Immunoregulation Laboratory The Francis Crick Institute London UK

13. MRC ‐ University of Glasgow Centre for Virus Research Glasgow UK

14. Montana State University Bozeman Montana USA

15. Center for Immunology and Department of Microbiology and Immunology University of Minnesota Minneapolis Minnesota USA

16. The Ragon Institute of Massachusetts General Hospital Massachusetts Institute of Technology, and Harvard University Cambridge Massachusetts USA

17. Lovelace Biomedical Research Institute Albuquerque New Mexico USA

18. Department of Medical Microbiology and Immunology University of Alberta Edmonton Alberta Canada

19. Department of Laboratory Medicine and Department of Immunology Yale University School of Medicine New Haven Connecticut USA

20. Department of Integrative Structural and Computational Biology The Scripps Research Institute La Jolla California USA

21. Institute of Virology, Freiburg University Medical Center, Faculty of Medicine University of Freiburg Freiburg Germany

22. Division of Biological Sciences University of California, San Diego La Jolla California USA

23. Department of Infectious Disease Imperial College London London UK

24. Department of Microbiology and Immunology Emory University School of Medicine Atlanta Georgia USA

25. Department of Microbiology and Immunology, WHO Collaborating Centre for Reference and Research on Influenza at the Peter Doherty Institute for Infection and Immunity University of Melbourne at The Peter Doherty Institute for Infection and Immunity Melbourne Victoria Australia

26. Department of Epidemiology University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

27. Department of Microbiology‐Immunology, School of Medicine Northwestern University Feinberg Chicago Illinois USA

28. Pediatric Scientist Development Program University of Pittsburgh Medical Center (UPMC) Children's Hospital of Pittsburgh Pittsburgh Pennsylvania USA

Abstract

AbstractRespiratory viruses are a common cause of morbidity and mortality around the world. Viruses like influenza, RSV, and most recently SARS‐CoV‐2 can rapidly spread through a population, causing acute infection and, in vulnerable populations, severe or chronic disease. Developing effective treatment and prevention strategies often becomes a race against ever‐evolving viruses that develop resistance, leaving therapy efficacy either short‐lived or relevant for specific viral strains. On June 29 to July 2, 2022, researchers met for the Keystone symposium “Respiratory Viruses: New Frontiers.” Researchers presented new insights into viral biology and virus–host interactions to understand the mechanisms of disease and identify novel treatment and prevention approaches that are effective, durable, and broad.

Funder

National Institutes of Health

Wellcome Trust

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

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