Melatonin sensitizes human breast cancer cells to ionizing radiation by downregulating proteins involved in double-strand DNA break repair

Author:

Alonso-González Carolina1,González Alicia1,Martínez-Campa Carlos1,Gómez-Arozamena José2,Cos Samuel1

Affiliation:

1. Department of Physiology and Pharmacology; School of Medicine; University of Cantabria and Instituto de Investigación Valdecilla (IDIVAL); Santander Spain

2. Department of Medical Physics; School of Medicine; University of Cantabria; Santander Spain

Funder

Spanish Science Technology and Innovation Ministry

Instituto de Investigación Valdecilla

Publisher

Wiley

Subject

Endocrinology

Reference64 articles.

1. Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture;Hill;Cancer Res,1988

2. Melatonin and mammary pathological growth;Cos;Front Neuroendocrinol,2000

3. Melatonin as a chronobiotic/anticancer agent: cellular, biochemical and molecular mechanisms of action and their implications for circadian-based cancer therapy;Blask;Curr Top Med Chem,2002

4. Melatonin and mammary cancer: a short review;Sánchez-Barceló;Endocr Relat Cancer,2003

5. Estrogen-signaling pathway: a link between breast cancer and melatonin oncostatic actions;Cos;Cancer Detect Prev,2006

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