Severely compromised supply of patch test allergens in Europe hampers adequate diagnosis of occupational and non‐occupational contact allergy. A European Society of Contact Dermatitis (ESCD), European Academy of Allergy and Clinical Immunology (EAACI), European Academy of Dermatology and Venereology (EADV) task forces ‘Contact Dermatitis’ and ‘Occupational Skin Disease’ position paper

Author:

John Swen Malte1ORCID,Bonertz Andreas2ORCID,Zimmer Julia2ORCID,Aerts Olivier3ORCID,Bauer Andrea4ORCID,Bova Maria5ORCID,Brans Richard1ORCID,Del Giacco Stefano6ORCID,Dickel Heinrich7ORCID,Corazza Monica8ORCID,Crépy Marie‐Noëlle9ORCID,Gallo Rosella10ORCID,Garcia‐Abujeta Jose Luis11ORCID,Giménez‐Arnau Ana Maria12ORCID,Klimek Ludger13ORCID,Lepoittevin Jean‐Pierre14ORCID,Ljubojević Hadžavdić Suzana15ORCID,Matura Mihaly16ORCID,Mortz Charlotte Gotthard17ORCID,Özkaya Esen18ORCID,Pesonen Maria19ORCID,Raison‐Peyron Nadia20ORCID,Rustemeyer Thomas21ORCID,Skudlik Christoph1ORCID,Spiewak Radoslaw22ORCID,Stingeni Luca23ORCID,Suomela Sari19ORCID,Symanzik Cara1ORCID,Taylor James24ORCID,Torres Maria25ORCID,Uter Wolfgang26ORCID,White Ian27ORCID,Wilkinson Mark28ORCID,Mahler Vera2ORCID,Johansen Jeanne Duus29ORCID

Affiliation:

1. Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) and Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University Osnabrück Germany

2. Paul‐Ehrlich‐Institut, Allergology Division Langen Germany

3. University Hospital Antwerp (UZA) and University of Antwerp Antwerp Belgium

4. Department of Dermatology University Allergy Center, University Hospital Carl Gustav Carus, Technical University Dresden Dresden Germany

5. Department of Internal Medicine A.O.R.N. Antonio Cardarelli Naples Italy

6. Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology University Hospital “Duilio Casula”, University of Cagliari Cagliari Italy

7. Department of Dermatology Venereology and Allergology, St. Josef Hospital, University Medical Center, Ruhr University Bochum Bochum Germany

8. Section of Dermatology, Department of Medical Sciences University of Ferrara Ferrara Italy

9. Department of Occupational and Environmental Diseases University Hospital of Centre of Paris, Hotel‐Dieu Hospital, AP‐HP Paris France

10. Section of Dermatology, Department of Health Sciences University of Genoa and Ospedale Policlinico San Martino, IRCCS Genoa Italy

11. Allergy Section, Marina Baixa Hospital Villajoyosa Spain

12. Department of Dermatology Hospital del Mar Research Institute, Universitat Pompeu Fabra Barcelona Spain

13. Center for Rhinology and Allergology Wiesbaden Germany

14. Laboratoire de Dermatochimie, University of Strasbourg, Institut Le Bel Strasbourg France

15. Department of Dermatology and Venereology University Hospital Center Zagreb, School of Medicine University of Zagreb Zagreb Croatia

16. Department of Dermatology Skaraborg Hospital Skövde Sweden

17. Department of Dermatology and Allergy Centre Odense University Hospital, University of Southern Denmark Odense Denmark

18. Department of Dermatology and Venereology Istanbul Faculty of Medicine, Istanbul University Istanbul Turkey

19. Finnish Institute of Occupational Health, Occupational Medicine Helsinki Finland

20. Department of Dermatology Montpellier University Hospital and Montpellier University Montpellier France

21. Department of Dermatology‐Allergology and Occupational Dermatology Amsterdam University Medical Centers Amsterdam The Netherlands

22. Department of Experimental Dermatology and Cosmetology Jagiellonian University Medical College Krakow Poland

23. Section of Dermatology, Department of Medicine and Surgery University of Perugia Perugia Italy

24. Department of Dermatology Cleveland Clinic and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Ohio USA

25. Allergy Unit, IBIMA‐Regional University Hospital of Malaga, UMA, RETICS ARADyAL, BIONAND Malaga Spain

26. Department of Medical Informatics Biometry and Epidemiology, University of Erlangen Erlangen Germany

27. Department of Cutaneous Allergy St. John's Institute of Dermatology, Guy's Hospital London UK

28. Leeds Teaching Hospitals NHS Trust Leeds UK

29. National Allergy Research Centre, Department of Skin and Allergy University of Copenhagen, Gentofte Hospital Copenhagen Denmark

Abstract

AbstractPatch testing is the only clinically applicable diagnostic method for Type IV allergy. The availability of Type IV patch test (PT) allergens in Europe, however, is currently scarce. This severely compromises adequate diagnostics of contact allergy, leading to serious consequences for the affected patients. Against this background, the European Society of Contact Dermatitis (ESCD) has created a task force (TF) (i) to explore the current availability of PT substances in different member states, (ii) to highlight some of the unique characteristics of Type IV vs. other allergens and (iii) to suggest ways forward to promote and ensure availability of high‐quality patch testing substances for the diagnosis of Type IV allergies throughout Europe. The suggestions of the TF on how to improve the availability of PT allergens are supported by the ESCD, the European Academy of Allergy and Clinical Immunology, and the European Academy of Dermatology and Venereology and intend to provide potential means to resolve the present medical crisis.

Publisher

Wiley

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