Clinicoradiologic features of ameloblastomas: A single‐centre study of 155 cases

Author:

Smit Chané1ORCID,Robinson Liam1ORCID,Ker‐Fox Jason2ORCID,Fonseca Felipe Paiva13ORCID,van Heerden Willie F. P.1ORCID,Uys André4ORCID

Affiliation:

1. Department of Oral and Maxillofacial Pathology, School of Dentistry, Faculty of Health Sciences University of Pretoria Pretoria South Africa

2. Private Statistician Cape Town South Africa

3. Department of Oral Surgery and Pathology, School of Dentistry Federal University of Minas Gerais (UFMG) Belo Horizonte Brazil

4. Department of Anatomy, School of Medicine, Faculty of Health Sciences University of Pretoria Pretoria South Africa

Abstract

AbstractBackgroundThe purpose of the current study was to report on the clinical presentation and radiologic features of 155 cases of ameloblastoma (AB), representing a detailed, large, single‐centre radiologic study.MethodsHistologically confirmed cases were reviewed over 11 years. Demographic and clinical data were retrieved from the patient's records. Radiologic information was analysed from available radiographs. The radiologic features of ABs were assessed according to the mean age of presentation and the mean duration of the lesion. The distinguishing radiologic features between adults/children and sex were also evaluated.ResultsA statistically significant correlation existed between loss of border demarcation and advanced mean age. Multilocular lesions were markedly more common in adults compared to children. Multilocular ABs were associated with increased lesion duration and advanced mean age. Radiologic signs of reactive bony changes associated with the tumour presented at the highest mean duration of all bony effects. Bony expansion and cortical destruction were statistically correlated with lesion duration. Tooth impaction was more common in children. Some mandibular lesions reached a significant size, resulting in impingement of the maxillary sinus, zygoma, orbit and pterygoid plates.ConclusionDue to unfortunate healthcare access constraints, ABs grow to significant sizes and exhibit features not often reported in the literature. The findings of this analysis highlighted the radiologic features of ABs expressed through the mean age and duration of the lesion. This emphasises the significance of timely management of these lesions.

Publisher

Wiley

Subject

Periodontics,Cancer Research,Otorhinolaryngology,Oral Surgery,Pathology and Forensic Medicine

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