GMP synthase is essential for viability and infectivity ofTrypanosoma bruceidespite a redundant purine salvage pathway

Author:

Li Qiong1,Leija Christopher1,Rijo-Ferreira Filipa234,Chen Jun5,Cestari Igor6,Stuart Kenneth6,Tu Benjamin P.5,Phillips Margaret A.1

Affiliation:

1. Department of Pharmacology; University of Texas Southwestern Medical Center at Dallas; 6001 Forest Park Rd Dallas TX 75390-9041 USA

2. Instituto de Medicina Molecular; Faculdade de Medicina; Universidade de Lisboa; Lisboa Portugal

3. Department of Neuroscience; University of Texas Southwestern Medical Center at Dallas; 6001 Forest Park Rd Dallas TX 75390-9041 USA

4. Graduate Program in Areas of Basic and Applied Biology; Instituto de Ciências Biomédicas Abel Salazar; Universidade do Porto; Porto Portugal

5. Department of Biochemistry; University of Texas Southwestern Medical Center at Dallas; 6001 Forest Park Rd Dallas TX 75390-9041 USA

6. Seattle Biomedical Research Institute; 307 Westlake Avenue North, Suite 500 Seattle WA 98109-5219 USA

Funder

National Institutes of Health

Welch Foundation

Fundação para a Ciência e a Tecnologia

Publisher

Wiley

Subject

Molecular Biology,Microbiology

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