Effect of Tacrine-3-caffeic Acid, A Novel Multifunctional Anti-Alzheimer's Dimer, Against Oxidative-Stress-Induced Cell Death in HT22 Hippocampal Neurons: Involvement of Nrf2/HO-1 Pathway

Author:

Chao Xiao-Juan1,Chen Zi-Wei1,Liu An-Min2,He Xi-Xin3,Wang Shao-Gui1,Wang Yu-Ting1,Liu Pei-Qing1,Ramassamy Charles4,Mak Shing-Hung5,Cui Wei5,Kong Ah-Ng6,Yu Zhi-Ling7,Han Yi-Fan58,Pi Rong-Biao1

Affiliation:

1. Department of Pharmacology & Toxicology; School of Pharmaceutical Sciences; Sun Yat-Sen University; Guangzhou China

2. Department of Neurosurgery; Sun Yat-Sen Memorial Hospital; Sun Yat-Sen University; Guangzhou China

3. Department of Traditional Chinese Medicine Chemistry; College of Chinese Materia Madica; Guangzhou University of Chinese Medicine; Guangzhou China

4. INRS-Institut Armand Frappier; Laval QC Canada

5. Department of Applied Biology and Chemical Technology; Hong Kong Polytechnic University; Hong Kong China

6. Department of Pharmaceutics; Ernest Mario School of Pharmacy; Rutgers, The State University of New Jersey; Piscataway NJ USA

7. Research & Development Division; School of Chinese Medicine; Hong Kong Baptist University; Hong Kong China

8. State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation); Hong Kong Polytechnic University; Shenzhen China

Funder

National Scientific Foundation Committee of China

Guangdong Provincial International Cooperation Project of Science & Technology

Publisher

Wiley

Subject

Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology

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