Hypothalamic endoplasmic reticulum stress as a key mediator of obesity-induced leptin resistance

Author:

Ye Z.12ORCID,Liu G.3,Guo J.1,Su Z.12

Affiliation:

1. Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine, Key Unit of Modulating Liver to Treat Hyperlipemia SATCM (State Administration of Traditional Chinese Medicine); Guangdong Pharmaceutical University; Guangzhou China

2. Guangdong Engineering Research Center of Natural Products and New Drugs; Guangdong Pharmaceutical University; Guangzhou China

3. Shenzhen Center for Disease Control and Prevention; Shenzhen China

Funder

National Natural Science Foundation of China

Science and Technology Planning Project of Yunfu, Guangdong, China

Guangzhou Science Technology Innovation Commission, China

Science and Technology Planning Project of Guangdong, China

Publisher

Wiley

Subject

Public Health, Environmental and Occupational Health,Endocrinology, Diabetes and Metabolism

Reference215 articles.

1. World Health Organization Obesity and overweight 2017 http://www.who.int/mediacentre/factsheets/fs311/en/

2. Obesity;Gonzalez-Muniesa;Nat Rev Dis Primers,2017

3. Global burden of obesity in 2005 and projections to 2030;Kelly;Int J Obes (Lond),2008

4. Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis;Lee;Autophagy,2016

5. Obesity is more closely related with hepatic steatosis and fibrosis measured by transient elastography than metabolic health status;Huh;Metabolism,2017

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