Non‐metabolic function of MTHFD2 activates CDK2 in bladder cancer
Author:
Affiliation:
1. Department of Urology The First Hospital of China Medical University Shenyang China
Publisher
Wiley
Subject
Cancer Research,Oncology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.15159
Reference29 articles.
1. Extensive heterogeneity in somatic mutation and selection in the human bladder
2. Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2
3. Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
4. Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy
5. Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications
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