N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1α signalling axis

Author:

Zhuang Changshui1ORCID,Zhuang Chengle1,Luo Xiaomin1,Huang Xinbo1,Yao Lv2,Li Jianfa1,Li Yawen1,Xiong Tiefu1,Ye Jing1,Zhang Fangting1,Gui Yaoting1

Affiliation:

1. The Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics; Peking University Shenzhen Hospital, Institute of Urology of Shenzhen PKU-HKUST Medical Center; Shenzhen P.R. China

2. Assisted Reproduction Unit, Department of Obstetrics and Gynecology; Sir Run Run Shaw Hospital, Zhejiang University School of Medicine; Hangzhou P.R. China

Funder

Guangdong Key Laboratory of Male Reproductive Medicine and Genetics

Shenzhen Project of Science and Technology

“San-ming” Project of Medicine in Shenzhen

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference45 articles.

1. 2004 WHO classification of the renal tumors of the adults;Lopez-Beltran;Eur Urol,2006

2. The genetic basis of kidney cancer: a metabolic disease. Nature reviews;Linehan;Urology,2010

3. Understanding the Warburg effect: the metabolic requirements of cell proliferation;Vander Heiden;Science (New York, N.Y.),2009

4. Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma;Simonnet;Carcinogenesis,2002

5. Metabolic reprogramming in clear cell renal cell carcinoma;Wettersten;Nat Rev Nephrol,2017

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3