Psychiatric comorbidities in adults with sickle cell disease: A narrative review

Author:

Mishkin Adrienne D.12ORCID,Prince Elizabeth J.3ORCID,Leimbach Elizabeth J.1,Mapara Markus Y.2,Carroll C. Patrick3ORCID

Affiliation:

1. Department of Psychiatry Columbia University Irving Medical Center New York New York USA

2. Blood and Marrow Transplantation Program, Department of Medicine Columbia University Irving Medical Center New York New York USA

3. Department of Psychiatry and Behavioral Sciences Johns Hopkins School of Medicine Baltimore Maryland USA

Abstract

SummaryAlthough descriptions of quality of life and patient reports of mood in sickle cell disease (SCD) have become more common in the literature, less is known about psychiatric illness prevalence, presentation, and treatment, particularly for adults. We provide a narrative review of what is known about common and debilitating psychiatric conditions such as depression, anxiety, and cognitive impairment, specifically for adults with SCD. We discuss the limitations of the current evidence, make provisional recommendations, and identify opportunities for research and improved care.

Publisher

Wiley

Subject

Hematology

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