Affiliation:
1. the Institute of Obstetrics and Gynaecology, University of London, Queen Charlotte's Hospital, Goldhawk Road, London, W.6
Abstract
Abstract
Aqueous extracts of human umbilical arteries and vein have been shown to contain a smooth muscle contracting substance. The active principle has been distinguished from smooth muscle contracting substances which are found in mammalian tissues, namely esters of choline, histamine, 5-hydroxytryptamine, bradykinin, angiotensin, and darmstoff. Evidence indicates that the smooth muscle stimulating activity of umbilical blood vessel extracts is due to a lipid-soluble unsaturated hydroxy acid. The possible physiological function of the active substance is discussed.
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Cited by
11 articles.
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