Aging‐related cell type‐specific pathophysiologic immune responses that exacerbate disease severity in aged COVID‐19 patients

Author:

Hou Yuan1,Zhou Yadi1,Jehi Lara23,Luo Yuan4,Gack Michaela U.5,Chan Timothy A.6,Yu Haiyuan78,Eng Charis191011,Pieper Andrew A.1213141516,Cheng Feixiong1911ORCID

Affiliation:

1. Genomic Medicine Institute Lerner Research Institute Cleveland Clinic Cleveland Ohio USA

2. Quantitative Health Sciences, Lerner Research Institute Cleveland Clinic Cleveland Ohio USA

3. Neurological Institute Cleveland Clinic Cleveland Ohio USA

4. Division of Health and Biomedical Informatics Department of Preventive Medicine Clinical and Translational Sciences Institute and Center for Health Information Partnerships Northwestern University Evanston Illinois USA

5. Florida Research and Innovation Center Cleveland Clinic Port Saint Lucie Florida USA

6. Center for Immunotherapy and Precision Immuno‐Oncology Cleveland Clinic Cleveland Ohio USA

7. Weill Institute for Cell and Molecular Biology Cornell University Ithaca New York USA

8. Department of Computational Biology Cornell University Ithaca New York USA

9. Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine Case Western Reserve University Cleveland Ohio USA

10. Department of Genetics and Genome Sciences Case Western Reserve University School of Medicine Cleveland Ohio USA

11. Case Comprehensive Cancer Center Case Western Reserve University School of Medicine Cleveland Ohio USA

12. Harrington Discovery Institute University Hospitals Cleveland Medical Center Cleveland Ohio USA

13. Department of Psychiatry Case Western Reserve University Cleveland Ohio USA

14. Geriatric Psychiatry GRECC Louis Stokes Cleveland VA Medical Center Cleveland Ohio USA

15. Institute for Transformative Molecular Medicine School of Medicine Case Western Reserve University Cleveland Ohio USA

16. Weill Cornell Autism Research Program Weill Cornell Medicine of Cornell University New York New York USA

Publisher

Wiley

Subject

Cell Biology,Aging

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