Acrolein, an endogenous aldehyde induces synaptic dysfunction in vitro and in vivo: Involvement of RhoA/ROCK2 pathway

Author:

Zhu Zeyu12,Lu Junfeng23,Wang Shuyi1,Peng Weijia2,Yang Yang1,Chen Chen2,Zhou Xin4,Yang Xifei5ORCID,Xin Wenjun4,Chen Xinyi6,Pi Jiakai7,Yin Wei4,Yao Lin8,Pi Rongbiao1910ORCID

Affiliation:

1. School of Medicine Sun Yat‐Sen University Guangzhou China

2. School of Pharmaceutical Sciences Sun Yat‐Sen University Guangzhou China

3. Department of Internal Medicine The Affiliated Tumor Hospital of Zhengzhou University Zhengzhou China

4. Zhongshan School of Medicine Sun Yat‐Sen University Guangzhou China

5. Key Laboratory of Modern Toxicology of Shenzhen Center for Disease Control and Prevention

6. School of Pharmaceutical Sciences South China Research Center for Acupuncture and Moxibustion Guangzhou University of Chinese Medicine Guangzhou China

7. Guangzhou Foreign Language School Guangzhou China

8. Research Institute of Acupuncture and Moxibustion Shandong University of Traditional Chinese Medicine Jinan China

9. International Joint Laboratory<SYSU‐PolyU HK> of Novel Anti‐Dementia Drugs of Guangzhou Guangzhou China

10. Guangdong Province Key Laboratory of Brain Function and Disease Sun Yat‐sen University Guangzhou China

Funder

Guangzhou Science, Technology and Innovation Commission

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Aging

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