Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC-Specific Chimeric Antigen Receptor-Reference-Cited by-同舟云学术

Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC-Specific Chimeric Antigen Receptor

Published:2017-02-06 Issue:4 Volume:17 Page:917-930
ISSN:1600-6135
Container-title:American Journal of Transplantation
language:en
Short-container-title:Am J Transplant

Author:

Noyan F.¹²,Zimmermann K.¹,Hardtke-Wolenski M.¹,Knoefel A.³,Schulde E.¹,Geffers R.⁴,Hust M.⁵,Huehn J.⁶,Galla M.⁷,Morgan M.⁷,Jokuszies A.⁸,Manns M. P.¹,Jaeckel E.¹²

Affiliation:

1. Department of Gastroenterology, Hepatology & Endocrinology; Hannover Medical School; Hannover Germany

2. Integrated Research and Treatment Center; Transplantation (IFB-Tx); Hannover Medical School; Hannover Germany

3. Department of Cardiothoracic, Transplantation and Vascular Surgery; Hannover Medical School; Hannover Germany

4. RG of Genome Analytics; Helmholtz Centre for Infection Research; Braunschweig Germany

5. Department of Biotechnology; Institute for Biochemistry, Biotechnology and Bioinformatics; Technische Universität Braunschweig; Braunschweig Germany

6. Department of Experimental Immunology; Helmholtz Centre for Infection Research; Braunschweig Germany

7. Institute of Experimental Haematology; Hannover Medical School; Hannover Germany

8. Department of Plastic, Aesthetic, Hand and Reconstructive Surgery; Hannover Medical School; Hannover Germany

Funder

German Federal Ministry of Education and Research

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/ajt.14175/fullpdf

Reference40 articles.

1. Regulatory immune cells in transplantation;Wood;Nat Rev Immunol,2012

2. Enrichment of regulatory T cells in acutely rejected human liver allografts;Taubert;Am J Transplant,2012

3. Hepatic infiltrates in operational tolerant patients after liver transplantation show enrichment of regulatory T cells before proinflammatory genes are down-regulated;Taubert;Am J Transplant,2016

4. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation;Edinger;Nat Med,2003

5. Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes;Joffre;Nat Med,2008

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