Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study-Reference-Cited by-同舟云学术

Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study

Published:2023-10-25 Issue: Volume: Page:
ISSN:1354-523X
Container-title:Oral Diseases
language:en
Short-container-title:Oral Diseases

Author:

Gilligan Gerardo¹^ORCID,Panico René¹^ORCID,Lazos Jerónimo¹^ORCID,Morelatto Rosana²^ORCID,Belardinelli Paola²^ORCID,Criscuolo Maria Ines²^ORCID,Bolesina Nicolas²^ORCID,Molina Ávila Ignacio³^ORCID,Pimentel Solá Juan Martin³^ORCID,Rivarola Emilce⁴,Morgante Maria Jimena⁴,Ingrassia Tonelli Maria Eugenia⁵^ORCID,Gimenez Javier⁶^ORCID,Doratti Pablo⁶,Werner Laura Cecilia⁷^ORCID,Prado‐Ribeiro Ana Carolina⁸⁹^ORCID,Brandão Thais Bianca⁸^ORCID,Vechiato‐Filho Aljomar Jose⁸⁹^ORCID,Cuzzullin Maria Claudia⁹^ORCID,Saldivia‐Siracusa Cristina⁹^ORCID,Lopes Marcio Ajudarte⁹^ORCID,Agostini Michelle¹⁰^ORCID,Romañach Mario José¹⁰^ORCID,Abrahão Aline Corrêa¹⁰^ORCID,Fonsêca Thamyres Campos¹⁰^ORCID,Kaminagakura Estela¹¹^ORCID,Anbinder Ana Lia¹¹^ORCID,Santos Alves Kamilla¹¹^ORCID,de Almeida Lança Maria Leticia¹¹^ORCID,Sacsaquispe‐Contreras Sonia¹²^ORCID,Rodriguez Ibazetta Karem¹²^ORCID,Gerber‐Mora Roberto¹³^ORCID,Aranda Romo Saray¹⁴^ORCID,Tejeda Nava Francisco Javier¹⁴^ORCID,Cordero‐Torres Karina¹⁵^ORCID,Moreno Silva Ricardo¹⁵,Gonzalez‐Arriagada Wilfredo¹⁶^ORCID,Toro Raiza¹⁷^ORCID,Silveira Felipe Martins¹⁸^ORCID,Gonzalez Natalia¹⁸,Vargas Pablo Agustin⁹^ORCID,Santos‐Silva Alan Roger⁹^ORCID,Bologna‐Molina Ronell¹⁸^ORCID,Villarroel‐Dorrego Mariana¹⁷^ORCID,Martinez Benjamin¹⁹^ORCID,Piemonte Eduardo¹^ORCID

Affiliation:

1. Oral Medicine Department “A”, Facultad de Odontología Universidad Nacional de Córdoba Córdoba Argentina

2. Oral Medicine Department “B”, Facultad de Odontología Universidad Nacional de Córdoba Córdoba Argentina

3. Hospital Señor del Milagro Salta Argentina

4. Hospital Luis C. Lagomaggiore Mendoza Argentina

5. University Hospital Universidad Nacional de Cuyo Mendoza Argentina

6. Private Centre La Plata Argentina

7. Hospital Aleman Buenos Aires Argentina

8. Dental Oncology Service, Instituto do Câncer do Estado de São Paulo (ICESP) Fundação da Faculdade de Medicina da Universidade de São Paulo (FMUSP) São Paulo Brazil

9. Oral Diagnosis Department, Piracicaba Dental School University of Campinas Piracicaba Brazil

10. Department of Oral Diagnosis and Pathology, School of Dentistry Federal University of Rio de Janeiro Rio de Janeiro Brazil

11. Department of Biosciences and Oral Diagnosis, Institute of Science and Technology São Paulo State University (Unesp) São José dos Campos Brazil

12. Facultad de Estomatología Universidad Peruana Cayetano Heredia Lima Peru

13. Oroclínica, Private Centre San José Costa Rica

14. Facultad de Estomatología Universidad Autónoma de San Luis de Potosí San Luis Potosi Mexico

15. Facultad de Odontología Universidad de Valparaíso Valparaiso Chile

16. Facultad de Odontología Universidad de los Andes Santiago Chile

17. Instituto de Investigaciones Odontológicas, Facultad de Odontología Universidad Central de Venezuela Caracas Venezuela

18. Oral Medicine and Oral Pathology Diagnosis Department, Facultad de Odontología Universidad de la República UDELAR Montevideo Uruguay

19. Oral Pathology Department, Facultad de Odontología Universidad Mayor de Chile Santiago de Chile Chile

Abstract

AbstractObjectiveTo determine the frequency of oral squamous cell carcinoma (OSCC) associated or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and traditional risk factors in Latin America.MethodsA retrospective observational study was conducted in 17 Latin American centres. There were included cases of OSCC, analysing age, gender, OSCC and their association with previous OPMD. Clinicopathological variables were retrieved. The condition of sequential‐OSCC versus OSCC‐de novo (OSCC‐dn) was analysed concerning the aforementioned variables. Quantitative variables were analysed using Student's t‐test, and qualitative variables with chi‐square.ResultsIn total, 2705 OSCC were included with a mean age of 62.8 years old. 55.8% were men. 53.75% of the patients were smokers and 38% were common drinkers. The lateral tongue border was the most affected site (24.65%). There were regional variations in OPMD, being leukoplakia the most frequent. Of the overall 2705 OSCC cases, 81.4% corresponded to OSCC‐dn, while s‐OSCC were 18.6%. Regarding lip vermillion SCC, 35.7% corresponded to de novo lip SCC and 64.3% were associated with previous OPMD.ConclusionsIn Latin America, OSCC‐dn seems to be more frequent with regional variations of some clinical and histopathological features. Further prospective studies are needed to analyse this phenomenon.

Publisher

Wiley

Subject

General Dentistry,Otorhinolaryngology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/odi.14778

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