Functional characterization of 22 novel CYP2D6 variants for the metabolism of Tamoxifen
Author:
Affiliation:
1. Department of Pharmacology, School of Pharmacy of Wenzhou Medical University, Wenzhou, Zhejiang, China
2. The Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics Ministry of Health, Beijing, China
Abstract
Funder
National Health and Family Planning Commission of the People's Republic of China
National Natural Science Foundation of China
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/68/6/819/36227812/jphp12556.pdf
Reference25 articles.
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3. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry;Zanger;Naunyn Schmiedebergs Arch Pharmacol,2004
4. Binding of bufuralol, dextromethorphan, and 3,4-methylenedioxymethylamphetamine to wild-type and F120A mutant cytochrome P450 2D6 studied by resonance Raman spectroscopy;Bonifacio;Biochem Biophys Res Commun,2006
5. Influence of CYP2D6 polymorphisms on serum levels of tamoxifen metabolites in Spanish women with breast cancer;Zafra-Ceres;Int J Med Sci,2013
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