IgG-mediated down-regulation of IgE bound to mast cells: a potential novel mechanism of allergen-specific desensitization

Author:

Uermösi C.1,Zabel F.2,Manolova V.1,Bauer M.3,Beerli R. R.3,Senti G.2,Kündig T. M.2,Saudan P.1,Bachmann M. F.24

Affiliation:

1. Cytos Biotechnology AG; Zurich-Schlieren Switzerland

2. Department of Dermatology; Zurich University Hospital; Zurich Switzerland

3. Intercell AG; Schlieren Switzerland

4. The Jenner Institute; University of Oxford; Headington Oxford UK

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference34 articles.

1. IgE in allergy and asthma today;Gould;Nat Rev Immunol,2008

2. The epidemic of allergy and asthma;Holgate;Nature,1999

3. Intergenerational 20 year trends in the prevalence of asthma and hay fever in adults: the Midspan family study surveys of parents and offspring;Upton;BMJ,2000

4. Clearance of IgE from serum of normal and hybridoma-bearing mice;Haba;J Immunol,1985

5. IgE receptor and signal transduction in mast cells and basophils;MacGlashan;Curr Opin Immunol,2008

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