Myeloid cell‐specific mutation of <i>Spi1</i> selectively reduces <scp>M2</scp> ‐biased macrophage numbers in skeletal muscle, reduces age‐related muscle fibrosis and prevents sarcopenia-Reference-Cited by-同舟云学术

Myeloid cell‐specific mutation of Spi1 selectively reduces M2 ‐biased macrophage numbers in skeletal muscle, reduces age‐related muscle fibrosis and prevents sarcopenia

Published:2022-09-13 Issue:10 Volume:21 Page:
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Wang Ying¹²,Welc Steven S.³⁴^ORCID,Wehling‐Henricks Michelle⁵,Kong Ying¹⁶,Thomas Connor⁵,Montecino‐Rodriguez Enca⁶,Dorshkind Kenneth⁶,Tidball James G.¹⁵⁶^ORCID

Affiliation:

1. Molecular, Cellular & Integrative Physiology Program University of California Los Angeles California USA

2. CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China

3. Department of Anatomy, Cell Biology & Physiology Indiana University School of Medicine Indianapolis Indiana USA

4. Indiana Center for Musculoskeletal Health Indiana University School of Medicine Indianapolis Indiana USA

5. Department of Integrative Biology and Physiology University of California Los Angeles California USA

6. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California Los Angeles California USA

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute on Aging

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.13690

Reference45 articles.

1. Proinflammatory Macrophages Enhance the Regenerative Capacity of Human Myoblasts by Modifying Their Kinetics of Proliferation and Differentiation

2. Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis

3. Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli

4. A Special Population of Regulatory T Cells Potentiates Muscle Repair

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