Affiliation:
1. Division of Exercise Physiology and Metabolism, BaySpo–Bayreuth Center of Sport Science University Bayreuth Bayreuth Germany
2. Exercise Physiology, Training & Training Therapy Research Group, Institute of Human Movement Science, Sport and Health University of Graz Graz Austria
3. Interdisciplinary Metabolic Medicine Trials Unit, Division of Endocrinology and Diabetology Medical University of Graz Graz Austria
4. Department of Pediatrics and Adolescent Medicine, Division of General Pediatrics Medical University Graz Graz Austria
Abstract
AbstractAimTo investigate the safety and efficacy of track and field training compared with intensification of insulin treatment only in adolescents with type 1 diabetes (T1D).Materials and MethodsEighteen adolescents (seven females) with T1D were included (age 15.1 ± 1.1 years, HbA1c 7.3% ± 1.0% [56.3 ± 10.9 mmol/mol]). After a 4‐week observational control phase, participants were randomized to either stand‐alone intensive glycaemic management (IT; telemedicine or on‐site visits, three times/week) or additionally performed track and field exercise (EX; three 60‐minute sessions/week) for 4 weeks. Glycaemia was assessed via continuous glucose monitoring during observational control and intervention phases.ResultsTime in range (70‐180 mg/dL; 3.9‐10.0 mmol/L) significantly improved from the observational control phase to the exercise intervention phase in EX (69% ± 13% vs. 72% ± 11%, P = .049), but not in IT (59% ± 22% vs. 62% ± 16%, P = .399). Time below range 1 (54‐69 mg/dL; < 3.9 mmol/L) improved in IT (3.1% ± 1.9% vs. 2.0% ± 0.8%, P = .017) and remained stable in EX (2.0% ± 1.7 vs. 1.9% ± 1.1%, P = .999). The EX group's HbA1c ameliorated preintervention to postintervention (mean difference: ΔHbA1c −0.19% ± 0.17%, P = .042), which was not seen within the IT group (ΔHbA1c −0.16% ± 0.37%, P = .40). Glucose standard deviation was reduced significantly in EX (55 ± 11 vs. 51 ± 10 mg/dL [3.1 ± 0.6 vs. 2.8 ± 0.6 mmol/L], P = .011), but not in IT (70 ± 24 vs. 63 ± 18 mg/dL [3.9 ± 1.3 vs. 3.5 ± 1.0 mmol/L], P = .186).ConclusionTrack and field training combined with intensive glycaemic management improved glycaemia in adolescents with T1D, which was not observed in the non‐exercise group.
Funder
Studienstiftung des Deutschen Volkes
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine