Contact allergy in Danish children: Current trends

Author:

Simonsen Anne B.12ORCID,Foss‐Skiftesvik Majken H.2,Thyssen Jacob P.2,Deleuran Mette3,Mortz Charlotte G.4,Zachariae Claus2,Skov Lone2,Osterballe Morten5,Funding Anne6,Avnstorp Christian7,Andersen Bo L.8,Vissing Susanne9,Danielsen Anne10,Dufour Nathalie11,Nielsen Niels H.12,Thormann Henrik13,Sommerlund Mette3,Johansen Jeanne D.1

Affiliation:

1. National Allergy Research Centre, Department of Dermatology and Allergy University of Copenhagen, Herlev and Gentofte Hospital Gentofte, Denmark

2. Department of Dermatology and Allergy University of Copenhagen Herlev and Gentofte Hospital Gentofte, Denmark

3. Department of Dermatology and Venereology Aarhus University Hospital Aarhus Denmark

4. Department of Dermatology and Allergy Centre Odense University Hospital Odense Denmark

5. Dermatology Clinic Herning Denmark

6. Dermatology Clinic Aalborg Øst Denmark

7. Dermatology Clinic Rødovre Denmark

8. Dermatology Clinic Svendborg Denmark

9. Dermatology Clinic Hørsholm Denmark

10. Dermatology Clinic Copenhagen Denmark

11. Dermatology Clinic Kalundborg Denmark

12. Dermatology Clinic Bagsværd Denmark

13. Dermatology Clinic Vejle Denmark

Abstract

BackgroundContact allergy is common in children, but may be underdiagnosed. Importantly, the clinical relevance of specific allergies is subject to constant change, and it is therefore important to continuously monitor the trends and changes of contact allergies in the paediatric population.ObjectivesTo identify possible changes in contact allergy and allergic contact dermatitis among Danish children referred for patch testing.MethodsA retrospective study was performed based on patch test data from the Danish National Database of Contact allergy. The current data were compared with previously published data on Danish children referred for patch testing.ResultsBetween 2012 and 2016, 1573 children and adolescents were patch tested. Overall, 385 (24.5%) had at least 1 positive patch test reaction. The overall prevalence was similar in boys and girls, across age groups, and in patients with and without atopic dermatitis. Statistically significant increases in contact allergy to fragrances and isothiazoliones were seen, whereas a decrease in nickel allergy was found.ConclusionAllergic contact dermatitis continues to be a common disease in children, and is even significantly increasing for some allergens.

Funder

National Board of Health's pool

Publisher

Wiley

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