Hepatitis B virus haplotype number at baseline is a predictive marker of functional cure during antiviral therapy for patients with genotypes A and D HBeAg ‐positive chronic hepatitis B

Author:

Wagner Josef12,Yuen Lilly13,Littlejohn Margaret1,Sozzi Vitina1,Jackson Kathy1,Martin Ross4,Aeschbacher Thomas4,Suri Vithika4,Tan Susanna K.4,Feierbach Becket4,Gaggar Anuj4,Marcellin Patrick5,Buti Ferret Maria6,Janssen Harry L. A.7,Gane Ed8,Meagher Niamh3,Price David J.39,Wong Darren110,Thompson Alexander T.10,Revill Peter A.1311ORCID

Affiliation:

1. Victorian Infectious Diseases Reference Laboratory Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity Melbourne Victoria Australia

2. Department of Paediatrics University of Melbourne Melbourne Victoria Australia

3. Department of Infectious Diseases University of Melbourne at the Peter Doherty Institute for Infection and Immunity Melbourne Victoria Australia

4. Gilead Sciences Foster City California USA

5. Hôpital Beaujon University of Paris Clichy France

6. Liver Unit Valle d'Hebron (Ciberehd) University Hospital Barcelona Spain

7. Toronto Center for Liver Diseases, Toronto General Hospital, University: Health Network University of Toronto Toronto Ontario Canada

8. New Zealand Liver Transplant Unit Auckland City Hospital Auckland New Zealand

9. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health The University of Melbourne Melbourne Victoria Australia

10. Department of Gastroenterology St. Vincent's Hospital Melbourne Victoria Australia

11. Department of Microbiology and Immunology University of Melbourne at the Peter Doherty Institute for Infection and Immunity Melbourne Victoria Australia

Funder

Gilead Sciences

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference36 articles.

1. World Health Organization.Progress report on HIV viral hepatitis and sexually transmitted infections 2021: accountability for the global health sector strategies 2016–2021: actions for impact [Internet].2021. Available from:https://www.who.int/publications/i/item/9789240027077. Accessed 1 Jun 2022.

2. World Health Organization.Hepatitis B.2021. Available from:https://www.who.int/news‐room/fact‐sheets/detail/hepatitis‐b. Accessed 1 Jun 2022.

3. How Do We Determine Whether a Functional Cure for HBV Infection Has Been Achieved?

4. Durability of Spontaneous and Treatment-Related Loss of Hepatitis B s Antigen

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