Healthcare resource utilization prior to suicide death or suicide attempt in patients with major depressive disorder—A Danish registry‐based cohort study

Author:

Jensen Kristoffer Jarlov1ORCID,Osler Merete23,Bødker Nikolaj4,Riise Jesper4,Petersen Janne15

Affiliation:

1. Copenhagen Phase IV Unit (Phase4Cph), Center for Clinical Research and Prevention & Department of Clinical Pharmacology Bispebjerg and Frederiksberg Hospital Frederiksberg Denmark

2. Section for Data, Biostatistics and Pharmacoepidemiology, Center for Clinical Research and Prevention Bispebjerg and Frederiksberg Hospital Frederiksberg Denmark

3. Section for Epidemiology, Institute for Public Health University of Copenhagen Copenhagen Denmark

4. Janssen Cilag A/S Birkerød Denmark

5. Section of Biostatistics, Department of Public Health University of Copenhagen Copenhagen Denmark

Abstract

AbstractIntroductionMajor depressive disorder (MDD) is associated with suicide events and with increased healthcare resource utilization (HRU). The aim was to analyze the pattern of HRU prior to death by suicide or suicide attempt in patients with MDD using national registries.MethodsDanish adults with MDD, who died by suicide or had a first‐time suicide attempt, were matched with MDD controls on age, sex, and MDD severity and analyzed for psychiatric and non‐psychiatric hospital and private practitioner contacts, and prescriptions 1 year prior to the event. For individuals having a second suicide attempt, HRU prior to first and second suicide attempt was analyzed.ResultsAmong 1061 individuals dying by suicide and 3759 individuals with suicide attempt, compared with their controls, the proportion with psychiatric hospitalization was more than 50% increased, mainly accounted for by acute contacts. The difference to the matched controls decreased with increasing MDD severity. Non‐psychiatric HRU was increased as well. The proportion with psychiatric hospitalizations or ED visits was reduced prior to the second attempt compared with first attempt.ConclusionAmong individuals with MDD, psychiatric and non‐psychiatric HRU was increased 1 year prior to suicide event. The proportion of individuals who had psychiatric HRU decreased from first to second suicide attempt.

Publisher

Wiley

Subject

Psychiatry and Mental health,Public Health, Environmental and Occupational Health,Clinical Psychology

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