PLAG1 immunohistochemistry is a sensitive marker for pleomorphic adenoma: a comparative study with PLAG1 genetic abnormalities

Author:

Katabi Nora1,Xu Bin1ORCID,Jungbluth Achim A1,Zhang Lei1,Shao Sung Y1,Lane Jason1,Ghossein Ronald1,Antonescu Cristina R1

Affiliation:

1. Department of Pathology; Memorial Sloan-Kettering Cancer Center; New York NY USA

Funder

National Institutes of Health

National Cancer Institute

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Reference27 articles.

1. Consistent PLAG1 and HMGA2 abnormalities distinguish carcinoma ex-pleomorphic adenoma from its de-novo counterparts;Katabi;Hum. Pathol.,2015

2. Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations;Kas;Nat. Genet.,1997

3. Aberrant PLAG1 expression in pleomorphic adenomas of the salivary gland: a molecular genetic and immunohistochemical study;Matsuyama;Virchows Arch.,2011

4. Conserved mechanism of PLAG1 activation in salivary gland tumors with and without chromosome 8q12 abnormalities: identification of SII as a new fusion partner gene;Astrom;Cancer Res.,1999

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