Detection of Three Genetic Polymorphisms in the 5′-Flanking Region and Intron 1 of Human CYP1A2 in the Japanese Population

Author:

Chida Michihiro,Yokoi Tsuyoshi,Fukui Takafumi,Kinoshita Moritoshi,Yokota Jun,Kamataki Tetsuya

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference18 articles.

1. Human cytochrome P-450PA (P-450IA2), the phenacetin O -deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N -oxidation of carcinogenic arylamines;Butler;Proc. Natl. Acad. Sci. USA,1989

2. A high-spin form of cytochrome P-450 highly purified from polychlorinated biphenyl-treated rats. Catalytic characterization and immunochemical quantitation in liver microsomes;Kamataki;Mol. Pharmacol.,1983

3. Species difference in N-hydroxylation of a tryptophan pyrolysis product in relation to mutagenic activation;Yamazoe;Cancer Res.,1981

4. Metabolism of 2-acetylaminfluorene and benzo[a]pyrene and activation of food-derived heterocyclic amine mutagens by human cytochrome P-450;McManus;Cancer Res.,1990

5. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites;Butler;Pharmacogenetics,1992

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