The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy-Reference-Cited by-同舟云学术

The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy

Published:2018-05-21 Issue:6 Volume:59 Page:1166-1176
ISSN:0013-9580
Container-title:Epilepsia
language:en
Short-container-title:Epilepsia

Author:

Baker Erin M.¹,Thompson Christopher H.¹,Hawkins Nicole A.¹,Wagnon Jacy L.²,Wengert Eric R.³,Patel Manoj K.³,George Alfred L.¹,Meisler Miriam H.²,Kearney Jennifer A.¹

Affiliation:

1. Department of Pharmacology; Northwestern University Feinberg School of Medicine; Chicago IL USA

2. Department of Human Genetics; University of Michigan; Ann Arbor MI USA

3. Department of Anesthesiology; University of Virginia Health System; Charlottesville VA USA

Funder

Feinberg School of Medicine

National Institute of Neurological Disorders and Stroke

Pharmaceutical Research and Manufacturers of America Foundation

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/epi.14196/fullpdf

Reference37 articles.

1. Estimating risk for developing epilepsy: a population-based study in Rochester, Minnesota;Hesdorffer;Neurology,2011

2. Sodium channel mutations in epilepsy and other neurological disorders;Meisler;J Clin Invest,2005

3. ILAE classification of the epilepsies: position paper of the ILAE Commission for Classification and Terminology;Scheffer;Epilepsia,2017

4. Hammer MF Wagnon JL Mefford HC SCN8A-related epilepsy with encephalopathy Pagon RA Adam MP Ardinger HH GeneReviews Seattle, WA University of Washington, Seattle

5. Recurrent and non-recurrent mutations of SCN8A in epileptic encephalopathy;Wagnon;Front Neurol,2015

Cited by 54 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Candesartan restores blood–brain barrier dysfunction, mitigates aberrant gene expression, and extends lifespan in a knockin mouse model of epileptogenesis;Clinical Science;2024-09

2. Persistent sodium currents in neurons: potential mechanisms and pharmacological blockers;Pflügers Archiv - European Journal of Physiology;2024-07-05

3. Complex biophysical changes and reduced neuronal firing in an SCN8A variant associated with developmental delay and epilepsy;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-06

4. Research Status, Synthesis and Clinical Application of Antiepileptic Drugs;Current Medicinal Chemistry;2024-02

5. From diagnosis to treatment in genetic epilepsies: Implementation of precision medicine in real-world clinical practice;European Journal of Paediatric Neurology;2024-01