Affiliation:
1. Department of Blood Transfusion, the First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China
Abstract
AbstractAdiponectin, as an indispensable regulator of the immune system, is the most abundant adipokine and is mainly produced by white adipose tissue. Adiponectin mediates the positive effects on systemic metabolism by regulating associated downstream signalling pathways; however, accumulating evidence shows that adiponectin plays an important role in regulating the function of innate and adaptive immune cells in the development of obesity and its related diseases. In this review, we focus on the biological function of adiponectin in regulating innate and adaptive immunity and outline the key role of adiponectin in various metabolic diseases, which will highlight a potential direction for adiponectin‐based therapeutic interventions for metabolic diseases.
Funder
National Natural Science Foundation of China
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Cited by
3 articles.
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