The Adverse Effects of Sorafenib in Patients with Advanced Cancers
Author:
Affiliation:
1. Department of Pharmacology; School of Chemical Biology & Pharmaceutical Sciences; Capital Medical University; Beijing China
2. Department of Pathology; McGill University; Montreal QC Canada
Funder
Beijing Science Foundation
Publisher
Wiley
Subject
Pharmacology,Toxicology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12365/fullpdf
Reference71 articles.
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3. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5;Liu;Cancer Res,2006
4. Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling;Wilhelm;Mol Cancer Ther,2008
5. Sorafenib in advanced hepatocellular carcinoma;Llovet;N Engl J Med,2008
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