The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine

Author:

Bonnefille Philippe,Sezgin-Bayindir Zerrin,Belkhelfa Haouaria,Arellano Cécile,Gandia Peggy,Woodley John,Houin Georges

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference49 articles.

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2. Cytochrome P450-mediated metabolism in the human gut wall;Thelen;J. Pharm. Pharmacol.,2009

3. Is the role of the small intestine in first-pass metabolism overemphasized?;Lin;Pharmacol. Rev.,1999

4. The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?;Doherty;Clin. Pharmacokinet.,2002

5. Medicinal importance of grapefruit juice and its interaction with various drugs;Kiani;Nutr. J.,2007

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3. Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors;Drug Metabolism and Disposition;2017-04-10

4. Presystemic and First-Pass Metabolism;Drug Delivery;2016-03-25

5. Challenges of Drug Delivery;Engineering Polymer Systems for Improved Drug Delivery;2014-01-17

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