Comparativein vitroand experimentalin vivostudies of the anti-epidermal growth factor receptor antibody nimotuzumab and its aglycosylated form produced in transgenic tobacco plants
Author:
Affiliation:
1. Center for Genetic Engineering and Biotechnology (CIGB); Playa; Havana; Cuba
2. Center of Molecular Immunology (CIM); Playa; Havana; Cuba
3. Center of Isotopes; Havana; Cuba
Publisher
Wiley
Subject
Plant Science,Agronomy and Crop Science,Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/pbi.12006/fullpdf
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4. Phase I clinical trial of the anti-EGFR monoclonal antibody nimotuzumab with concurrent external thoracic radiotherapy in Canadian patients diagnosed with stage IIb, III or IV non-small cell lung cancer unsuitable for radical therapy;Bebb;Cancer Chemother. Pharmacol.,2011
5. Trends in glycosylation, glycoanalysis and glycoengineering of therapeutic antibodies and Fc-fusion proteins;Beck;Curr. Pharm. Biotechnol.,2008
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