Pig-to-baboon heterotopic heart transplantation - exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens-Reference-Cited by-同舟云学术

Pig-to-baboon heterotopic heart transplantation - exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens

Published:2015-04-03 Issue:3 Volume:22 Page:211-220
ISSN:0908-665X
Container-title:Xenotransplantation
language:en
Short-container-title:Xenotransplantation

Author:

Iwase Hayato¹,Ekser Burcin¹²,Satyananda Vikas¹,Bhama Jay³,Hara Hidetaka¹,Ezzelarab Mohamed¹,Klein Edwin⁴,Wagner Robert⁴,Long Cassandra¹,Thacker Jnanesh³,Li Jiang¹,Zhou Hao¹⁵,Jiang Maolin¹⁵,Nagaraju Santosh¹,Zhou Huidong¹⁵,Veroux Massimiliano²,Bajona Pietro¹,Wijkstrom Martin¹,Wang Yi⁵,Phelps Carol⁶,Klymiuk Nikolai⁷,Wolf Eckhard⁷,Ayares David⁶,Cooper David K. C.¹

Affiliation:

1. Thomas E. Starzl Transplantation Institute; University of Pittsburgh; Pittsburgh PA USA

2. Department of Surgery, Transplantation and Advanced Technologies; Vascular Surgery and Organ Transplant Unit; University Hospital of Catania; Catania Italy

3. Department of Cardiothoracic Surgery; University of Pittsburgh; Pittsburgh PA USA

4. Division of Laboratory Animal Resources; University of Pittsburgh; Pittsburgh PA USA

5. Center for Kidney Transplantation; Second Affiliated Hospital of the University of South China; Hengyang Hunan China

6. Revivicor; Blacksburg VA USA

7. Gene Center; Ludwig Maximilians Universitat Munchen (LMU); Munich Germany

Funder

National Institutes of Health

Publisher

Wiley

Subject

Transplantation,Immunology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/xen.12167/fullpdf

Reference49 articles.

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2. Production of alpha 1,3-galactosyltransferase-deficient pigs;Phelps;Science,2003

3. Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience;Kuwaki;Nat Med,2005

4. alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months;Tseng;Transplantation,2005

5. The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients;Ezzelarab;Transplantation,2009

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